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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FILIP1L All Species: 13.03
Human Site: S421 Identified Species: 35.83
UniProt: Q4L180 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q4L180 NP_001035924.1 1135 130382 S421 K L E V E K L S K R I M A L E
Chimpanzee Pan troglodytes XP_516621 1352 154470 S421 K L E V E K L S K R I M A L E
Rhesus Macaque Macaca mulatta XP_001090550 1135 130382 S421 K L E V E K L S K R I M A L E
Dog Lupus familis XP_535715 1130 129897 N418 K L E V E K L N K R I M A L D
Cat Felis silvestris
Mouse Mus musculus Q6P6L0 1131 129754 S419 K L E V D K L S V R I T A L E
Rat Rattus norvegicus Q8K4T4 1212 137734 Q428 R L E V E K L Q K R M S E L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519034 1137 129557 N421 K V E V D K L N K R I M E L E
Chicken Gallus gallus XP_419877 1176 134725 Q428 K L E V E K L Q K R M S E L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A3KNA5 1129 129722 N413 K A E V D K L N H R I M E L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 98.1 92.2 N.A. 87.8 44.4 N.A. 78.7 46 N.A. 57.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 83.8 98.7 95.5 N.A. 93.4 62.7 N.A. 86.9 64.8 N.A. 74.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 66.6 N.A. 73.3 73.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 80 N.A. 93.3 80 N.A. 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 0 0 0 0 0 0 0 56 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 100 0 67 0 0 0 0 0 0 0 45 0 89 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 % I
% Lys: 89 0 0 0 0 100 0 0 78 0 0 0 0 0 0 % K
% Leu: 0 78 0 0 0 0 100 0 0 0 0 0 0 100 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 23 67 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 45 0 0 0 23 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % T
% Val: 0 12 0 100 0 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _